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Dysplastic nevus : ウィキペディア英語版 | Dysplastic nevus
A dysplastic nevus or atypical mole is a nevus (mole) whose appearance is different from that of common moles. In 1992, the NIH recommended that the term "dysplastic nevus" be avoided in favor of the term "atypical mole". An atypical mole may also be referred to as an atypical melanocytic nevus, atypical nevus, B-K mole, Clark's nevus, dysplastic melanocytic nevus, or nevus with architectural disorder. Dysplastic nevi often grow to larger than ordinary moles, and may have irregular and indistinct borders. Their color may not be uniform, and may range from light pink to very dark brown. They usually begin as flat, but parts may raise above the skin surface. See ABCDE and "ugly duckling" characteristics below. Dysplastic nevi can be found anywhere, but are most common on the trunk in men, and on the calves in women. ==Cancer== According to the National Cancer Institute, researchers have shown that atypical moles are more likely than ordinary moles to develop into a type of skin cancer called melanoma. It is worth noting that the vast majority of atypical moles will never become malignant. However, numerous studies indicate that about half of melanomas arise from atypical moles. Evidence supporting this connection arises from clinical photodocumentation of evolving lesions, patient self-reports of changing lesions, pathology studies showing dysplastic nevi in histologic contiguity with melanoma, and epidemiology studies indicating that about half of individuals affected by melanoma also have atypical moles. Epidemiology studies have also shown that individuals with multiple dysplastic nevi are at much higher risk for developing melanomas. Because of this, moles should be checked regularly by a doctor or nurse specialist, especially if they look complex; grow larger; or change in color, or shape; or if ''any'' changes occur, such as itching, flaking or oozing.
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